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Primal Queen vs. Liver Pills vs. Multivitamins vs. Hormone Blends vs. Greens Powders: The Ultimate Women’s Supplement Showdown

AK
ByAnnmarie KyleJan 20, 2026In Partnership With Primal Queen

As a physician with over 25 years in internal medicine, I talk to women every day who just feel off. Low energy. Mood swings. Bloating. Irregular cycles. Or just that sense that your body isn’t cooperating anymore..

If you’ve tried a bunch of supplements already, you’re not alone. The market is overflowing with options — but most don’t fix the issue I see most often in practice: women are depleted in foundational nutrients like iron, B vitamins, zinc, folate, and vitamin A.

So I looked at the 5 supplement types women ask me about most — and here’s what actually stands out. Let’s get into it.

Foundation First: Which One Replenishes What Women Are Missing?

Most women don’t need another “hormone hack.” They need raw materials. That’s why Primal Queen is the one I recommend most often.

It’s made from six grass-fed beef organs, including uterus, ovaries, and fallopian tubes, plus liver, heart, and kidney. That blend naturally provides heme iron, retinol (true vitamin A), B12, natural folate, zinc, selenium, and CoQ10 in forms the body can actually absorb and use.

In practice, this matters because:

  • Heme iron absorbs better than plant-based iron
  • Retinol is more usable than beta-carotene
  • Natural folate behaves differently than folic acid

Winner: Primal Queen for true nutrient repletion.

Bioavailability: Which One Actually Absorbs Well?

One of the biggest frustrations I hear is: “I’ve been taking supplements for months… why don’t I feel different?” Often, it’s because the form matters as much as the dose. This is where a lot of women get stuck.

Drugstore multivitamins often use synthetic forms (like non-heme iron and folic acid) that don’t absorb as well — and can be harder on digestion.

That’s where Primal Queen is different. It delivers nutrients in a whole-food matrix, meaning the body recognizes them and can utilize them more efficiently.

Winner: Primal Queen
Runner Up: Thorne Hormone Advantage

Hormone Support: Which One Makes the Most Difference?

This is where marketing gets confusing. A lot of products sell “hormone support,” but hormones are ultimately built from raw materials. If the body doesn’t have a nutrient foundation, it can’t regulate smoothly.

This is why Primal Queen tends to be my top recommendation for women who want hormone rhythm support — not because it’s a “hormone supplement,” but because it replenishes the nutrients that help the body function as designed.

In practice, women often notice improvements in:

  • steadier energy
  • calmer cravings
  • skin clarity
  • fewer dips around their cycle
  • more predictable rhythm over time

Winner: Primal Queen
Runner Up: Thorne Hormone Advantage

Breadth: Which Option Is Most Complete?

Liver pills can help, as the liver is rich in iron, B12, and vitamin A.

But liver-only formulas are limited. You’re missing nutrients found in the heart and kidney (like CoQ10 and selenium), plus the female organ focus that many women prefer for cycle rhythm support.

Winner: Primal Queen
Runner Up: Liver pills

Ease of Use: Which One Fits Real Life?

If a supplement isn’t easy, most people won’t stick with it. That’s just real life.

Primal Queen is two peppermint-scented capsules daily — no taste, no prep, no mixing, no powders, no weird textures. It’s one of the simplest routines I’ve seen women stick with long-term.

Winner: Primal Queen
Runner Up: Drugstore Vitamins

Final Verdict: The One I Recommend Most Often

Most women don’t need more supplements. They need better nourishment — in forms the body can actually use.

That’s why, after years of reviewing products and tracking patient feedback, Primal Queen is the supplement I recommend most often for women who want steady energy, mood stability, and cycle rhythm support.

If you’ve been “doing everything right” and still feel stuck, the missing piece might not be effort. It might be nutrient replenishment.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.